Probability models for DNA evolution
 

We use the book Probability models for DNA sequence evolution by Rick Durrett. It is not
necessary to buy this book yourself; after seeing how many students follow the course, I will
make copies of the relevant chapters.

Examenation will be by means of a number of take-home exercises, which I subsequently
discuss individually which each of the students.

Copies of the relevant chapter of the book are available from monday, september 20. You can
get a copy from Maryke Titawano, in office S-338.
 

MATERIAL COVERED DURING LECTURES

september 17:  page 5-10 .
october 1: page 11-12; page 14-16, starting with "mutations"; page 18-21, from "Moran model"
until the statement of (2.17).
october 8: proof of (2.17); Section 1.3 until (3.2).
october 15: Section 1.3 until page 31; we have skipped the proof of (3.5) and will do
that proof next week.
october 22: Section 1.3 until page 35.
november 5: Section 1.4 until page 52; Section 2.1 until Example 1.2.
november 12: Section 2.1 until Example  1.4; Section 1.5 start.
november 19: Section 1.5 until page 61.
november 26:  Section 1.5 until page 64.
december 3: Finished Section 1.5; Section 3.1 until (1.20) (without proof).
december 10: Finish Section 3.1; Introduction to Section 3.2.

EXAM

For the take-home exam, click  here . If you want to have a grade before Christmas,  you need to
make the exam before december 17. You can return the exercises by email to me, or put
them in my mailbox. Write a telephone number and email address on the exam, so that I can
contact you for an appointment.

EXTRA CREDITS

Some students have acknowledged that they would like to get the oppertunity to get
3 extra credit points for this subject. Here follow the requirements for this:

1.  Write a short essay about the contents of Section 2.2 in the book (Recombination);
2. Find the paper  The genealogy of samples in models with selection by Krone and Neuhauser
    on the internet, and write a summary of the ideas and results in that paper.

Both exercises should take you about a week, so you should count on two weeks fulltime
work.